焦保卫，香港中文大学生化系环境科学哲学博士，现任中国科学院昆明动物研究所研究员，博士生导师，遗传资源与进化国家重点实验室副主任。

中文名：焦保卫

毕业院校：香港中文大学

职业：教育科研工作者

职称：研究员

1996.9-2000.7 西南大学（原西南师范大学）生命科学院理学学士

2000.9-2003.7 西南大学生命科学院动物学专业理学硕士

2003.9-2007.3 香港中文大学生化系环境科学哲学博士

2007.5-2008.10 香港中文大学中医学院任研究助理

2008.10-2013.4 马萨诸塞大学医学院（University of Massachusetts Medical school）博士后

2013.4- 中国科学院昆明动物研究所 研究员 发育的印迹调控与进化学科组负责人

焦保卫长期从事发育及生殖生物学研究，鉴定了RLIM基因在乳腺发育中的关键作用，发现X染色体失活（XCI）在成体细胞中的新模式，阐明了RLIM基因在乳腺发育和胚胎发育早期中调控机制及其进化意义。还通过一系列新基因的发现和功能研究揭示了鱼类生殖生长的新格局。已在Cell，Nature，Journal of Endocrinology，Journal of Cell Biochemistry，BBRC 等期刊杂志发表论文17篇。

承担科研项目

中科院昆明动物所启动经费 150万

国家自然科学基金面上项目 110万

代表论著

1. Jiao B., Taniguchi-Ishigaki N., Güng？r C., Peters MA., Chen YW., Riethdorf S., Drung A., Ahronian LG., Shin J., Pagnis R., Pantel K., Tachibana T., Lewis BC., Johnsen SA., Bach I. 2013. Functional activity of RLIM/Rnf12 is regulated by phosphorylation-dependent nucleo-cytoplasmic shuttling. Mol Biol Cell. In press

2. Jiao B., Ma H., Shokhirev M., Drung A., Yang Q., Shin J., Lu S., Byron M., Kalantry S., Mercurio AM, Lawrence JB, Hoffmann A. and Bach I. 2012. Paternal RLIM/Rnf12 is a survival factor for milk-producing alveolar cells. Cell. 149:630-41.

3. Li MH., Wu FR., Gu Y., Wang TR., Wang H., Yang SJ., Sun YL., Zhou LY., Huang XG., Jiao B., Cheng CH., Wang DS. 2012. Insulin-Like Growth Factor 3 Regulates Expression of Genes Encoding Steroidogenic Enzymes and Key Transcription Factors in the Nile Tilapia Gonad. Biology of Reproduction. 86:163, 1-10.

4. Shin J., Bossenz M., Chung Y., Ma H., Byron M., Taniguchi-Ishigaki N., Zhu X., Jiao B., Hall LL, Green MR, Jones SN, Hermans-Borgmeyer I, Lawrence JB and Bach I. 2010. Maternal Rnf12/RLIM is required for imprinted X-chromosome inactivation in mice. Nature. 467:977-81.

5. Lin ZX, Jiao B., Che CT., Zuo Z., Mok CF., Zhao M., Ho WK., Tse WP., Lam KY., Fan RQ., Yang ZJ and Cheng CH. 2010. Ethyl acetate fraction of the root of Rubia cordifolia L. inhibits keratinocyte proliferation in vitro and promotes keratinocyte differentiation in vivo: potential application for psoriasis treatment. Phytotherapy Research. 24:1056-64.

6. Jiao B., Yeung E.K.C., Chan C.B. and Cheng C.H.K. 2008. Establishment of a transgenic yeast screening system for estrogenicity and identification of the anti-estrogenic activity of malachite green. Journal of Cellular Biochemistry.　105:1399-409.

7. Zhang Y., Liu Y., Huang X., Liu X., Jiao B., Meng Z., Zhu P., Li S., Lin H. and Cheng C.H.K. 2008. Two alternatively spliced GPR39 transcripts in seabream: molecular cloning, genomic organization, and regulation of gene expression by metabolic signals. Journal of Endocrinology. 199: 457-70.

8. Jiao B. and Cheng C.H.K. 2010. Disrupting actions of bisphenol A and malachite green on growth hormone receptor gene expression and signal transduction in seabream. Fish Physiology and Biochemistry. 36:251-61.

9. Wang D.S., Jiao B.*, Hu C., Huang X., Liu Z. and Cheng C.H.K. 2008. Discovery of a gonad-specific IGF subtype in teleost, Biochemical and Biophysical Research Communications. 367, 336-41.

10. Huang X., Jiao B.*, Fung K.K., Zhang Y., Chan C. B., Lin H., Wang D.S. and Cheng C.H.K. 2007. The presence of two distinct prolactin receptors with different signal pathways and constructive expression pattern under the stimulation of steroid hormones in teleost. Journal of Endocrinology. 194, 373-92.

11. Liu Z., Wu F., Jiao B.*, Zhang X., Hu C., Huang B., Zhou L., Huang X., Wang Z., Zhang Y., Nagahama Y., Cheng C.H.K. and Wang D.S. 2007. Molecular cloning of Dmrt1, Foxl2 and Cyp19 in Southern catfish and their possible roles in sex differentiation. Journal of Endocrinology 194, 223-41.

12. Jiao B., Huang X., Chan C.B., Zhang L., Wang D.S. and Cheng C.H.K. 2006. The co-existence of two growth hormone receptors in teleost fish and their differential signal transduction, tissue distribution and hormonal regulation of expression in seabream. Journal of Molecular Endocrinology 36, 23-40.